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目的:评价小剂量多巴酚丁胺对冠心病心室功能的影响及安全性。材料和方法:对47例冠心病进行小剂量多巴酚丁胺介入的平衡法放射性核素心室造影,并同20例对照组进行对比分析。结果:多巴酚丁胺介入后各组患者左心室收缩期和舒张期功能均有一定程度改善,心绞痛组改善最明显,其次为陈旧性心肌梗塞和急性心肌梗塞组,无一例因多巴酚丁胺副作用而停止试验。结论:小剂量多巴酚丁胺负荷试验有助于判定心肌缺血和心肌梗塞程度,对了解病情、估价心脏病的潜在功能具有一定的意义。
Objective: To evaluate the effect and safety of low-dose dobutamine on ventricular function in patients with coronary heart disease. MATERIALS AND METHODS: Balanced radionuclide ventriculography was performed in 47 patients with coronary heart disease under low-dose dobutamine exposure and compared with 20 control subjects. Results: After dobutamine intervention, systolic and diastolic function of left ventricle in each group improved to a certain degree, while in angina pectoris group was the most obvious improvement, followed by old myocardial infarction and acute myocardial infarction group. Butylamine side effects and stop the test. Conclusion: The low-dose dobutamine stress test can help determine the extent of myocardial ischemia and myocardial infarction. It is of great significance to understand the condition and evaluate the potential function of heart disease.