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目的分析脑梗死患者血小板计数(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW)、大血小板比率(P-LCR)的变化情况。方法比较脑梗死患者(ACI组,68例),短暂性脑缺血发作患者(TIA组,36例),健康体检者(对照组,100例)的PLT、MPV、PDW、P-LCR水平。结果 ACI组、TIA组PLT[(100.0±38.0)×10~9/L、(104.0±43.0)×10~9/L]低于对照组,MPV[(12.9±2.2)、(13.6±2.1)fl]、P-LCR[(45.1±11.1)%、(43.9±11.8)%]高于对照组(P<0.05)。结论动态观察血小板参数对脑梗死的诊断和治疗具有一定的临床意义。
Objective To analyze the changes of platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), and large platelet ratio (P-LCR) in patients with cerebral infarction. Methods The levels of PLT, MPV, PDW, P-LCR in cerebral infarction patients (ACI group, 68 cases), transient ischemic attack patients (TIA group, 36 cases) and healthy subjects (control group, 100 cases) were compared. Results Compared with control group, PLT [(100.0 ± 38.0) × 10 ~ 9 / L, (104.0 ± 43.0) × 10 ~ 9 / L] in ACI group and TIA group were significantly lower than those in control group fl], P-LCR [(45.1 ± 11.1)%, (43.9 ± 11.8)%] than those in the control group (P <0.05). Conclusions Dynamic observation of platelet parameters has certain clinical significance for the diagnosis and treatment of cerebral infarction.