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在 DNA 水平上进行 HLA 组织配型,比血清学方法更准确、快速,具有较强的临床实用价值。本文综述了 DNA 水平 HLA 配型的四种方法:PCR-RFLP、PCR-SSO、PCR-SSCP、 PCR-SSP,并阐述了其各自的特点。
HLA matching at the DNA level is more accurate and rapid than serological methods and has strong clinical practical value. In this paper, four methods for HLA matching at DNA level are summarized: PCR-RFLP, PCR-SSO, PCR-SSCP, PCR-SSP and their respective features.