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本文观察了42例脑动脉硬化症患者血清载脂蛋白E和B100含量的变化,发现两者均高于正常对照组,且呈直线正相关(r=0.71,P<0.01)。提示载脂蛋白E和B100可能是脑动脉硬化症的危险因素。P<0.01comparedwithcontrolgroup.3讨论动脉壁内脂质中含有载脂蛋白E和B100[2],而脂质代谢紊乱特别是载脂蛋白E和B100的同时升高是导致脑AS的重要因素,故载脂蛋白E和B100含量的变化作为脑AS和脑血管病的危险因素的研究日益受到重视,尤其是载脂蛋白E与脑AS的关系是近年来许多研究者注目的课题。本文通过42例脑AS患者及44例对照组载脂蛋白E和B100含量测定并对二者呈相关性进行研究发现,脑AS病人这两种载脂蛋白含量显著高于正常对照组,且二者呈直线正相关关系,表明对载脂蛋白E和B100的研究为脑AS危险性的诊断和防治能提供一个新途径。参考文献
In this paper, the changes of serum apolipoprotein E and B100 levels in 42 patients with cerebral arteriosclerosis were observed. Both of them were higher than the normal control group, and there was a linear positive correlation (r = 0.71, P <0.01). Tip Apolipoprotein E and B100 may be risk factors for cerebral arteriosclerosis. P <0.01comparedwithcontrolgroup. 3 discussion of arterial wall lipids containing apolipoprotein E and B100 [2], and lipid metabolism disorders, especially apolipoprotein E and B100 at the same time is an important factor leading to brain AS, so apolipoprotein E and The study of B100 content as a risk factor of cerebral AS and cerebrovascular disease is paid more and more attention. Especially, the relationship between apolipoprotein E and brain AS has been the focus of many researchers in recent years. In this paper, 42 cases of AS patients and 44 cases of control group apolipoprotein E and B100 levels were determined and the correlation between the two studies found that brain AS patients with two levels of apolipoprotein was significantly higher than the normal control group, and two Showed a linear positive correlation, indicating that the study of apolipoprotein E and B100 for the diagnosis and prevention of brain AS can provide a new way. references