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目的探讨两种不同麻醉诱导方法在老年肺癌患者麻醉中的应用,为老年患者麻醉提供更安全的麻醉诱导方式。方法选取2013年2月至2014年2月间收治的老年择期手术患者84例。随机分为两组,每组各42例患者。其中Ⅰ组采用单纯咪唑安定诱导法,Ⅱ组采用咪唑安定和异丙酚联合诱导法,分别对两组老年肺癌患者进行气管插管后全身麻醉。记录患者在诱导前、插导管前和插管后的血流动力学方面指标变化情况。结果用药后,Ⅱ组患者各时段平均动脉压差异有统计学意义(P<0.05)。Ⅱ组患者麻醉后并发症的发生率明显低于Ⅰ组患者,差异有统计学意义(P<0.05)。结论采用咪唑安定联合异丙酚进行老年患者的全身麻醉诱导的安全性更强,并发症更少,值得临床推广。
Objective To explore the application of two different methods of induction of anesthesia in elderly patients with lung cancer and provide safer ways to induce anesthesia in the elderly. Methods Eighty-four elderly patients undergoing elective surgery were selected from February 2013 to February 2014. Randomly divided into two groups, each group of 42 patients. Group Ⅰ was induced by midazolam alone. Group Ⅱ was induced by midazolam combined with propofol. The two groups of elderly patients with lung cancer underwent general anesthesia after tracheal intubation. Record patients before induction, catheterization and intubation before hemodynamic changes in the index. Results After treatment, the difference of mean arterial pressure in each group was statistically significant (P <0.05). The incidence of postoperative complications in group Ⅱ was significantly lower than that in group Ⅰ (P <0.05). Conclusion The induction of general anesthesia with midazolam combined with propofol is more safe and less complications, which is worthy of clinical promotion.