井岗霉素是上海市农药研究所创制的新农用抗菌素,可防治水稻纹枯病。现将40％井岗霉素A的毒性研究结果报道如下。大、小鼠经口和经皮LD_(50)均>10000mg/kg,对大鼠皮肤无刺激性;用剂量定期递增法,小鼠经口给药20天,蓄积系数为5.3; Jinggangmycin is a new agricultural antibiotic created by Shanghai Institute of Pesticide, which can prevent and control rice sheath blight. Now 40% Jinggangmycin A toxicity studies reported below. The mice were orally and transdermally administered with LD50 (50)> 10000mg / kg, which were not irritating to the skin of rats. The mice were orally administered for 20 days with a dose-escalation method with an accumulation coefficient of 5.3.