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目的 探讨高分子量细胞相关蛋白 (Highmolecularweightcell-associatedprotein ,HM·CAP)对幽门螺杆菌 (Hp)的诊断价值。方法 对 40例正常人及 12 0例胃部疾病病人进行了HM·CAP检测 ,对其中 116例病人同时进行14 C -尿素酶呼吸试验 (UBT)、Hp培养及病理组织学对比。结果 40例正常人中 ,有 7例HM·CAP阳性 ,14 0例病人中 ,78例阳性。我们以14 C -UBT、Hp培养及病理组织学来评估HM·CAP对Hp的诊断价值 ,其敏感性分别为 97 4%、10 0 %、97 3 % ,特异性为 94 7%、74 5 %、90 % ,诊断符合率为96 6%、88 8%、94 8%。结论 HM·CAP是一种具有较高敏感性及特异性的诊断Hp感染的方法。
Objective To investigate the diagnostic value of high molecular weight cell-associated protein (HM · CAP) in Helicobacter pylori (Hp). Methods 40 cases of normal subjects and 120 cases of gastric diseases were detected by HM · CAP. 116 patients were simultaneously subjected to 14 C - UBT test, Hp culture and histopathological comparison. Results Of the 40 normal subjects, 7 were HM · CAP positive, of which 14 of 14 were positive. We evaluated the diagnostic value of HM · CAP for Hp by 14 C -UBT, Hp culture and histopathology with sensitivity of 97 4%, 100%, 97 3%, specificity of 94 7%, 74 5 %, 90%, the diagnostic coincidence rate was 96 6%, 88 8%, 94 8%. Conclusion HM · CAP is a highly sensitive and specific method to diagnose Hp infection.