论文部分内容阅读
目的观察思密达、山莨菪碱(654-2)减少阿奇霉素副作用的效果。方法对66例下呼吸道感染患儿随机分为两组,治疗组34例,用山莨菪碱注射液与阿奇霉素注射液混合于同一液体瓶中静脉滴注,在每次静脉滴注前半个小时服用思密达,剂量≤3岁患儿1.5g,>3岁患儿3g;对照组32例单纯给予阿奇霉素静脉滴注,观察两组胃肠道反应(包括恶心、呕吐、腹痛、腹泻)的发生率。结果治疗组副作用的发生率低于对照组,且肺部啰音吸收快、住院天数短,差异具有显著性意义。结论山莨菪碱与思密达联合应用能减少阿奇霉素的胃肠道副作用,并能促进肺部病变愈合,值的儿科临床应用。
Objective To observe the effect of Smectite and Anisodamine (654-2) in reducing side effects of azithromycin. Methods 66 cases of children with lower respiratory tract infection were randomly divided into two groups, the treatment group of 34 cases, with anisodamine injection and azithromycin injection in the same liquid bottle intravenous infusion, half an hour before each intravenous infusion taking Smectite, 1.5g in children ≤ 3 years old and 3g in children> 3 years old; 32 cases in the control group were given azithromycin intravenously only to observe the gastrointestinal reactions (including nausea, vomiting, abdominal pain and diarrhea) in both groups rate. Results The incidence of side effects in the treatment group was lower than that in the control group, and the pulmonary rales absorbed fast and hospitalized days were short, the difference was significant. Conclusions Anisodamine combined with Smecta could reduce the gastrointestinal side effects of azithromycin and promote the healing of pulmonary lesions.