显微镜下自体角膜缘干细胞移植治疗翼状胬肉65例分析

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目的观察翼状胬肉切除联合自体角膜缘干细胞移植术的临床疗效。方法对65例(72只眼)翼状胬肉行显微镜切除,取同侧眼颞上方带角膜缘干细胞的球结膜移植于巩膜暴露区。结果随访6~36个月,平均13个月。角膜上皮5 d内修复。随访期有2只眼复发,复发率为2.78%。结论翼状胬肉切除联合自体角膜缘干细胞移植术可以提高治疗效果,降低复发率。 Objective To observe the clinical efficacy of excision of pterygium combined with limbal stem cell autografting. Methods Totally 65 cases (72 eyes) of pterygium were resected microscopically and the conjunctiva of corneal limbal stem cells in the ipsilateral eye was transplanted into the scleral exposed area. The results were followed up for 6 to 36 months, an average of 13 months. Corneal epithelial repair within 5 d. Follow-up period, 2 eyes had recurrence, the recurrence rate was 2.78%. Conclusion Pterygium resection combined with limbal stem cell transplantation can improve the therapeutic effect and reduce the recurrence rate.
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