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目的 观察β型转化生长因子（ＴＧＦβ１）基因修饰的Ｂ１０小鼠骨髓树突状细胞（ＤＣ）在Ｃ３Ｈ小鼠体内的迁移和存活，以探讨ＤＣ生物学特性与移植耐受性的关系。方法 从Ｂ１０小鼠骨髓分离ＤＣ前体细胞，在粒细胞巨噬细胞集落刺激因子＋β型转化生长因子（ＧＭ－Ｃ...
Objective To observe the migration and survival of B10 mouse bone marrow dendritic cells (DCs) modified by transforming growth factorβ1 (TGFβ1) gene in C3H mice to investigate the relationship between the biological characteristics of DCs and their tolerance to transplantation. Methods DC precursor cells were isolated from the bone marrow of B10 mice and cultured in the presence of granulocyte macrophage colony-stimulating factor + beta-type transforming growth factor (GM-C)