动脉插管注入抗癌药物治疗头颈部恶性肿瘤已近20年,通过各种药物的试用,虽然对一些恶性肿瘤收到较全身用药更为有效的缓解疗效,但迄今尚未见治愈的报告。我院自1962年采用此法治疗头颈部恶性肿瘤,曾单独用药治愈腭粘膜鳞状细胞癌1例。 病例介绍 高××,男,55岁,1965年7月27日住院。腭部肿物5个月,大如蚕豆,曾在外院行局部切除,术后1个月复发。有吸烟史30余年,每日约10支,饮酒少量,无家族肿瘤病史。查体,一般情况良好,口腔状况一般,硬腭几全为肿物占据,大小为4.5×3.5厘米,表面不平,覆以白色角化样组织,硬,固定(图1)。病理检查,镜下见瘤组织呈乳头状排列,表面可见不全角化,癌细胞大多分 The arterial cannula has been infused with anti-cancer drugs for the treatment of head and neck malignancy for nearly 20 years. Through trials of various drugs, although some malignant tumors have received more effective palliative effects than systemic administration, no cure has been reported so far. Our hospital has used this method for the treatment of head and neck malignancy since 1962. It has been used alone to cure one case of squamous cell carcinoma of the orbital mucosa. Case description Gao X, male, 55 years old, was hospitalized on July 27, 1965. The orbital mass was 5 months old and was as large as broad beans. It had been locally removed in the external hospital and recurred 1 month after operation. She has a history of smoking for more than 30 years, about 10 a day, a small amount of alcohol, and no family history of cancer. Physical examination, generally in good condition, general oral condition, hard palate is occupied by a tumor, the size is 4.5 × 3.5 cm, the surface is uneven, covered with white keratinoid tissue, hard, fixed (Figure 1). Pathological examination showed that the tumor tissue was papillary and the surface was incompletely keratinized. The cancer cells were mostly divided.