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本文根据近年活血化瘀防治冠心病中药研究工作中的初步体会,对于如何搞好中药研究工作进行了讨论。从整体水平研究活血化瘀对心血管系统的作用,从抗凝、溶栓及血流动力学角度研究对血液物理化学性状及某些成分的影响,以及从细胞和分子水平研究对体外培养心肌细胞的作用。这些工作初步表明,活血化瘀治则及其方药对循环系统具有复杂的调整作用,并发现对心肌细胞及某些最基本的生理活动有一定调整作用,从而部分的阐明了活血化瘀的作用原理。实践证明,在中医理论指导下,充分运用现代科学(特别是现代医学)的成果和手段,密切结合临床,建立较为合理的科研设想和工作假说,对于进一步加速中医中药研究工作是十分重要的。
This article is based on the preliminary understanding of the traditional Chinese medicine research on blood circulation prevention and treatment of coronary heart disease in recent years, and discusses how to do a good job in the study of traditional Chinese medicine. To study the effect of blood circulation on the cardiovascular system from the overall level, to study the effects of blood coagulation, thrombolysis, and hemodynamics on the physical and chemical properties of blood and certain components, and to study the effect of in vitro culture of cells on the level of cells and molecules. The role of cells. These work preliminary shows that the principle of promoting blood circulation and removing blood stasis and its prescriptions have a complex adjustment effect on the circulatory system, and it has been found to have a certain adjustment effect on myocardial cells and some of the most basic physiological activities, thus partially clarifying the role of blood circulation and stasis. principle. Practice has proved that under the guidance of traditional Chinese medicine theory, the full use of modern science (especially modern medicine) results and means, close integration with the clinical, and establish a more reasonable scientific research hypothesis and work hypothesis is very important to further accelerate the research work of traditional Chinese medicine.