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目的:比较康泉及康泉合用地塞米松预防急性白血病化疗所致的胃肠道反应的效果。方法:在同一方案的不同疗程,分别单用康泉或康泉合用地塞米松,随机对照,共观察110疗程。结果:康泉及康泉合用地塞米松对预防化疗所致急性呕吐有效率分别为69.5%和95.1%,有明显差异(P<0.01);对于迟发性呕吐两组的有效率分别为74.555%和91.83%,亦有明显差异。结论:康泉和地塞米松合用对控制急性和迟发性恶性呕吐优于康泉单用
OBJECTIVE: To compare the effects of Kangquan and Kangquan combined dexamethasone in preventing gastrointestinal reactions caused by acute leukemia chemotherapy. Methods: In different courses of the same protocol, dexamethasone was used alone with Kangquan or Kangquan, randomized control, and a total of 110 courses of treatment were observed. RESULTS: The combined use of dexamethasone and Kangquan and Kangquan was effective in preventing chemotherapy-induced acute vomiting, which was 69.5% and 95.1%, respectively (P<0.01). The effective rates were 74.555% and 91.83%, respectively. There were also significant differences. Conclusion: The combination of Kangquan and dexamethasone is superior to Kangquan alone in controlling acute and delayed malignant vomiting