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目的评价雷帕霉素药物涂层支架(CYPHER plus+,Cordis)治疗冠状动脉前降支长病变的长期临床疗效。方法前降支长病变(病变长度≥20mm)患者46例置入CYPHERplus+支架56个,病变长度20~45mm,平均(25.2±7.8)mm,术前病变狭窄程度(87.9±7.5)%;血管直径(3.0±0.75)mm。其中前降支病变>28mm10例,置入2个支架重叠,1个长支架覆盖病变36例。结果手术即刻成功率100%,术后造影病变残余狭窄(3.5±2.8)%,支架覆盖病变完全,支架近、远端无夹层,血流TIMI3级。随访6个月,心绞痛消失43例,术后6个月复查冠状动脉造影,无血管再狭窄发生。结论雷帕霉素药物涂层支架治疗前降支长病变是解决前降支长病变安全有效的方法 。
Objective To evaluate the long-term clinical efficacy of CYPHER plus + and Cordis in the treatment of coronary anterior descending coronary artery disease. METHODS: Forty-six patients with anterior descending coronary artery disease (length ≥20 mm) were enrolled in CYPHERplus + stent 56. The length of the lesion was 20-45 mm (average 25.2 ± 7.8 mm) and preoperative stenosis was 87.9 ± 7.5%. The vessel diameter (3.0 ± 0.75) mm. Among them, there were 10 cases of anterior descending coronary artery lesions> 28mm in diameter, 2 superposition stents and 1 long stent covered lesions in 36 cases. Results Immediate success rate was 100%. The residual stenosis of postoperative angiography was (3.5 ± 2.8)%. The lesions covered by the stent were completely covered. There was no dissection in the proximal and distal ends of the stent and TIMI grade 3 in the blood flow. Six months follow-up, angina pectoris disappeared in 43 cases and coronary angiography was performed 6 months after surgery. No vascular restenosis occurred. Conclusion Rapamycin-coated stent is an effective and safe method for the treatment of anterior descending coronary artery disease.