糖精是一种甜味物质,已有将近一百年的历史,为那些需要控制能量如糖尿病和体重过重的人等广泛摄食。它也用于甜化饮料等食品和某些化装品(例如牙膏、漱口水等)及药品(例如小儿科用的药液)。约于1950年前都认为糖精对人体是无害的。用大鼠进行的最早的慢性毒性研究结果是不确定的,1955年美国食品保护委员会确定“人的膳食中糖精的最大容许水平至少每日可高达1.0g”。 Sweeteners are a sweetening substance that has been around for nearly a century and is widely consumed by those who need to control energy such as diabetes and overweight. It is also used in foods such as sweetened drinks and some cosmetics (such as toothpaste, mouthwash, etc.) and medicines (such as pediatric medicines). About 1950, saccharin was considered harmless to the human body. The earliest chronic toxicity study conducted in rats was inconclusive. In 1955, the US Food Protection Commission determined that “the maximum allowable level of saccharin in human diet should be at least 1.0 g per day.”