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粉防己碱(Tetrandrine,Tet)具有降压作用,但其降压效果是否与血浆肾素活性(Plasma renin activity,PRA)有关尚无报道,本实验观察Tet对3种不同模型的高血压大鼠的降压作用,并用自发性高血压大鼠(SHR)研究其降压作用与PRA的关系。
Tetrandrine (Tet) has an antihypertensive effect, but whether its antihypertensive effect is related to plasma renin activity (PRA) has not been reported. This experiment observed Tet on three different models of hypertensive rats. The antihypertensive effect and the use of spontaneously hypertensive rats (SHR) to study the relationship between its antihypertensive effect and PRA.