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目的观察国产伏立康唑治疗恶性血液病患者侵袭性真菌感染(IFI)的临床疗效和安全性。方法以国产伏立康唑治疗6例发生于恶性血液病患者的侵袭性真菌感染,观察疗效及不良反应。结果6例患者中,有效4例,其中完全反应3例,部分反应1例。1例用药第6天出现低钾血症。结论国产伏立康唑是治疗恶性血液病患者侵袭性真菌感染的安全有效的药物。
Objective To observe the clinical efficacy and safety of domestic voriconazole in the treatment of invasive fungal infection (IFI) in patients with hematologic malignancies. Methods Voriconazole was used in the treatment of invasive fungal infection in 6 patients with hematologic malignancies. The curative effect and adverse reactions were observed. Results Of the 6 patients, 4 were effective, of which 3 were completely reaction and 1 was partial response. 1 case of hypokalemia occurred on the 6th day. Conclusion Domestic voriconazole is a safe and effective drug for the treatment of invasive fungal infections in patients with hematologic malignancies.