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滇南的实验结果显示,人工接种当地间日疟原虫子孢子后,经短潜伏期发病的38名志愿者,首次见虫时间为8-13d,首次见虫和临床初发时的原虫密度分别为0.2-1.6和0.6-4040个/μl。造成如此明显差异的原因,似与虫现期和临床初发间的时间距离密切有关,表现为感染后临床初发的时间越早,多数病例于首次见虫时的原虫密度越低,反之则高。文中讨论了这一问题在病原生物学和流行病学上的重要性。
The experimental results in southern Yunnan showed that the 38 volunteers who were infected with P. vivax in the local incubation period were 8-13 days old for the first time after artificial inoculation with sporozoites of Plasmodium vivax, 0.2-1.6 and 0.6-4040 / μl. The reason for such a significant difference seems to be closely related to the time interval between the present stage and initial stage of clinical manifestations. The earlier the clinical onset of infection is, the lower the protozoan density is in most cases when the worm is first seen, whereas the opposite high. This article discusses the issue of the etiology and epidemiology of the importance of.