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核苷(酸)类似物是目前临床上治疗乙型肝炎的重要药物,但应用过程中可出现乙型肝炎病毒的变异,从而发生耐药。本文就核苷(酸)类似物在乙型肝炎治疗方面的进展以及病毒耐药的新认识作一综述。
Nucleoside (acid) analogues is currently an important drug in the treatment of hepatitis B, but the application process may occur in Hepatitis B virus mutation, resulting in drug resistance. This article reviews the advances in the treatment of hepatitis B (nucleoside) analogues and the new understanding of virus resistance.