Synthesis and Crystal Structure of 1-Phenyl-3-methyl-4-(4-bromophenyl)-6-(2-chlorophenyl)- pyrazol

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The title compound (C25H17BrClN3) has been synthesized by the reaction of 1-(2- chlorophenyl)-3-(4-bromophenyl)-2-propylene-1-one with 5-amino-3-methyl-1-phenyl pyrazole under microwave irradiation and its structure was determined by single-crystal X-ray diffraction. The crystal is of triclinic, space group P1 with a = 9.3798(11), b = 10.6200(13), c = 11.7433(15) ?, α = 72.932(9), β = 78.877(10), γ = 72.045(9)o, V = 1057.0(2) ?3, Z = 2, Dc = 1.492 g/cm3, μ = 2.088 mm -1 , F(000) = 480, Mr = 474.78, the final R = 0.0428 and wR = 0.0879. X-ray analysis revealed that the dihedral angle between the pyrazol and pyridine planes is 6.45o. The title compound (C25H17BrClN3) has been synthesized by the reaction of 1- (2-chlorophenyl) -3- (4-bromophenyl) -2-propylene-1-one with 5-amino-3-methyl-1-phenyl pyrazole under microwave irradiation and its structure was determined by single-crystal X-ray diffraction. The crystal is of triclinic space group P1 with a = 9.3798 (11), b = 10.6200 (13), c = 11.7433 72.932 (9), β = 78.877 (10), γ = 72.045 (9) o, V = 1057.0 (2)? 3, Z = 2, Dc = 1.492 g / cm3, ) = 480, Mr = 474.78, the final R = 0.0428 and wR = 0.0879. X-ray analysis revealed that the dihedral angle between the pyrazol and pyridine planes is 6.45 o.
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