肝硬化门静脉高压症(CPH)并发外周血细胞减少的病因有三种,即脾脏因素(约占80%)、非脾脏因素(约占4%)和综合因素(约占16%).治疗方法包括非手术治疗和手术治疗.轻、中度外周血细胞减少适合非手术治疗,重度外周血细胞减少可行手术治疗.脾脏因素是CPH并发外周血细胞减少的的主要病因,但不是全部;治疗方法应根据外周血细胞减少的程度进行选择.“,”There are three causes of cirrhotic portal hypertension(CPH)complicated by peripher-al blood cytopenia:splenic factors(about 80%),non-splenic factors(about 4%)and comprehensive fac-tors(about 16%).The treatment includes non-surgical treatment and surgical treatment.Mild to moderate peripheral blood cell reduction is suitable for non-surgical treatment.Severe peripheral blood cytopenia is feasible to surgical treatment.Splenic factors are the main cause of peripheral cytopenia in CPH,but not all;The treatment method should be based on the degree of peripheral blood cytopenia.