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目的探讨质子泵抑制剂在消化性溃疡临床研究及应用。方法 2008年1月至2011年1月门诊诊治的消化性溃疡患者240例依据用药不同分为A组60例,B组60例,C组60例,D组60例,观察各组临床疗效。结果 A组应用奥美拉唑总有效率90.00%,B组应用泮托拉唑钠总有效率91.66%,C组应用口服雷贝拉唑钠总有效率93.33%,D组口服埃索美拉唑镁总有效率96.67。结论质子泵抑制剂在消化性溃疡临床效果确切,应用方便,种类齐全,副作用轻微。
Objective To investigate the clinical research and application of proton pump inhibitors in peptic ulcer. Methods From January 2008 to January 2011, 240 patients with peptic ulcer diagnosed as outpatients were divided into group A (60 cases), group B (60 cases), group C (60 cases) and group D (60 cases). The clinical efficacy of each group was observed. Results The total effective rate of omeprazole in group A was 90.00%. The total effective rate of pantoprazole sodium in group B was 91.66%. The total effective rate of oral rabeprazole sodium in group C was 93.33%. Group D received oral methadone Magnesium magnesium total efficiency of 96.67. Conclusions Proton pump inhibitors are effective in the treatment of peptic ulcer. They are easy to be applied, complete in variety and slight in side effects.