随着人类社会工业化的发展,重金属汞、镉、铅、铬以及类金属砷等污染物排放造成严重的环境污染和人类健康损害,但多数重金属致病机制仍没有被阐明。进入20世纪90年代,伴随人类基因组计划的实施,基因芯片技术应运而生,它具有与电子芯片相似的微型化和大规模分析、处理生物信息的 With the industrialization of human society, the discharge of pollutants such as heavy metals such as mercury, cadmium, lead, chromium and metalloid arsenic cause serious environmental pollution and human health damage. However, the pathogenesis of most heavy metals has not yet been clarified. Enter the 1990s, along with the implementation of the human genome project, gene chip technology came into being, it has the miniaturization and large-scale analysis similar to the electronic chip, dealing with biological information