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目的评价胸部高分辨率CT(HRCT)对早期发现结缔组织病所致肺间质病变的诊断价值。方法选择南京红十字医院及安徽医科大学附属医院2004年7月至2005年6月门诊及住院的系统性红斑狼疮患者20例、类风湿关节炎及干燥综合征患者共16例,行X线胸片及常规螺旋CT全胸扫描,运用HRCT对肺部扫描,进行对比分析。结果肺HRCT示21例(58.3%)患肺间质病变(ILD),常规螺旋CT示11例(30.6%)ILD,而X线全胸片仅4例(11.1%)示ILD。HRCT可见如蜂窝状阴影、胸膜下线影、小叶间隔增厚、毛玻璃样变等常规CT及X线胸片下无法观察到的征象。结论HRCT能充分显示肺间质纤维化的各种征象,对结缔组织病引起的肺间质病变的早期诊断有重要意义。
Objective To evaluate the diagnostic value of chest high resolution CT (HRCT) in the early detection of interstitial lung disease caused by connective tissue disease. Methods Twenty cases of systemic lupus erythematosus patients from Nanjing Red Cross Hospital and Affiliated Hospital of Anhui Medical University from July 2004 to June 2005 were enrolled in the study. Sixteen patients with rheumatoid arthritis and Sjogren’s syndrome were treated with X-ray chest Slice and conventional spiral CT chest scan, the use of HRCT on the lung scan, comparative analysis. Results Pulmonary HRCT showed ILD in 21 cases (58.3%), ILD in 11 cases (30.6%) in conventional spiral CT, and only 4 cases (11.1%) in X - ray showed ILD. HRCT can be seen as honeycomb shadow, subpleural line shadow, interlobular septal thickening, frosted glass and other conventional CT and X-ray can not be observed under the sign. Conclusion HRCT can fully display various signs of pulmonary fibrosis, which is of great significance for the early diagnosis of interstitial lung disease caused by connective tissue disease.