对３５例病脑患儿外周血Ｔ细胞及其亚群、血清免疫球蛋白水平等进行检测。结果表明，病脑急性期外周血ＣＤ＋３、ＣＤ＋４、ＣＤ＋８细胞百分率以及淋巴细胞转化率均显著低于正常对照组；血清ＩｇＡ、ＩｇＭ和ＩｇＧ均值较对照组明显降低或偏低；重型病脑组血清ＩｇＧ、ＩｇＡ、ＩｇＭ水平均显著低于轻型组，而Ｔ细胞及亚群等未见显著变化。提示病脑时Ｔ细胞及其亚群数量或功能降低；低免疫球蛋白状态、机体免疫功能的低下或紊乱是病脑发生、发展的重要因素。 Peripheral blood T cells and their subgroups and serum immunoglobulin levels were detected in 35 children with cerebral diseases. The results showed that the percentages of CD + 3, CD + 4, CD + 8 cells and lymphocyte transformation rate in peripheral blood were significantly lower than those in normal control group. The serum IgA, IgM and IgG were significantly lower or lower than those in control group. Serum IgG, IgA, IgM levels were significantly lower than the light group, while T cells and subgroups had no significant change. Prompt disease brain T cells and their subsets or reduce the number or function; low immunoglobulin state, the body’s immune function is low or disorder of the brain occurrence and development of an important factor.