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目的:了解泌尿系感染病原菌的分布及对常用药的敏感情况,为临床治疗泌尿系感染提供科学依据。方法:对分离的2 765株细菌用法国梅里埃公司VITEK-2细菌全自动鉴定仪进行鉴定和药敏试验,并对产ESBLS耐药表型的菌株用双纸片法进行确证。结果:2 765株病原菌,其中革兰阴性菌2 074株(75.01%),主要是大肠埃希菌,肺炎克雷伯菌,阴沟肠杆菌、变形杆菌,革兰阳性菌553株(20.00%),主要是表皮葡萄球菌、屎肠球菌。真菌138株(4.99%)。主要是白假丝酵母菌。结论:大肠埃希菌仍然是泌尿系感染的主要病原菌,病原菌的耐药率呈上升趋势,临床应重视尿培养。根据药敏试验合理使用抗菌药物。
Objective: To understand the distribution of urinary tract infection pathogens and sensitive to commonly used drugs for clinical treatment of urinary tract infection provide a scientific basis. Methods: The isolated 2 765 strains of bacteria were identified and susceptible tested by the VITEK-2 bacterial automatic analyzer of Merlot France. The ESBLS-resistant strains were confirmed by double disc method. Results: A total of 2 765 strains of pathogens, including 2 074 strains of Gram-negative bacteria (75.01%), mainly Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Proteus and Gram-positive bacteria were 553 (20.00% , Mainly Staphylococcus epidermidis, Enterococcus faecium. 138 fungi (4.99%). Mainly Candida albicans. Conclusion: Escherichia coli is still the main pathogen of urinary tract infection. The resistance rate of pathogens is on the rise. Urinary culture should be emphasized clinically. According to drug susceptibility testing reasonable use of antibacterial drugs.