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目的：观察无抽搐电休克（ MECT）治疗抑郁症的临床效果。方法将56例抑郁症患者随机分为治疗组和对照组各28例。治疗组采用MECT治疗。对照组采用氟西汀治疗。对比2组治疗前和治疗1、2、3周HAMD评分。对比2组不良反应发生情况。结果治疗前2组HAMD评分差异无统计学意义（P＞0．05）。治疗后第1、2、3周末2组HAMD评分逐渐降低，且治疗组低于对照组，差异均有统计学意义（ P＜0．05）。2组不良反应发生率均较轻，经对症处理后均缓解。结论改良无抽搐电休克治疗抑郁症起效快，疗效显著，不良反应少，尤其适用于中重度抑郁症患者。而在护理上必须重视心理护理防止消极意外事件的发生，同时做好电休克前后的护理工作。“,”Objective To observe the clinical effect of MECT in depression .Methods 56 cases patients with de-pression were randomly divided into treatment group and control group ,each of 28 cases.Treatment group were treated by MECT.Control group were treated by fluoxetine .After treatment,compared the HAMD score before and 1,2,3weeks after treat-ment.Compared the adverse reactions .Results The HAMD score before treatment in 2 groups has no statistically significant (P<0.05).The HAMD score 1,2,3weeks after treatment of 2 groups were reduced,and the treatment group was lower than that of control group,the difference was statistically significant(P<0.05).The adverse reactions of 2 groups were lightt,were relieved after symptomatic treatment .Conclusion Improved MECT treat depression has an good effect , and rapid onset has less adverse reactions ,especially for moderate to severe depression .While in the care we must pay attention to psychological care to prevent the occurrence of negative incidents ,while making care before and after the electric shock .