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目的探讨婴儿实体肿瘤的发病特点、治疗原则及预后。方法回顾性研究1995~2000年间68例婴儿实体肿瘤的病理类型、治疗方法和生存率及死亡原因。结果恶性肿瘤40例(58.8%),良性肿瘤多为畸胎瘤。恶性肿瘤手术切除率83.3%。29例接受化疗,其中79.3%予30%~70%的化疗减量。婴儿恶性肿瘤3年生存率66.7%,5年生存率45.4%。结论婴儿肿瘤的主要治疗手段为手术切除辅以术后化疗,适当的化疗减量必要、安全、有效。
Objective To investigate the characteristics of infant solid tumors, treatment principles and prognosis. Methods Retrospective study of 68 cases of infantile solid tumors from 1995 to 2000 pathological types, treatment and survival rates and causes of death. Results 40 cases of malignant tumors (58.8%), mostly benign tumors teratoma. Surgical resection rate of malignant tumors was 83.3%. 29 cases received chemotherapy, of which 79.3% to 30% to 70% of the chemotherapy reduction. Three-year survival rate of infant malignancies 66.7%, 5-year survival rate of 45.4%. Conclusion The main treatment of infant tumors is surgical resection supplemented with postoperative chemotherapy, appropriate chemotherapy reduction necessary, safe and effective.