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目的 :了解高血压病 (EH)患者并发腔隙性脑梗死时血流流变学变化的特点。方法 :采用北京R80型板式粘度计和毛细管法分别测定 33例脑梗死 ,32例EH患者和 2 0例对照组人血浆粘度、高切粘度、低切粘度和红细胞压积并进行对比分析。结果 :EH和梗死组患者血液粘滞度较正常对照组明显升高 (P <0 0 5～ 0 0 1) ,梗死组患者低切粘度、血浆粘度和红细胞压积较EH组改变更显著 (P <0 0 1)。结论 :血液粘滞度的异常升高可能是缺血性脑血管病的重要发病机制。
Objective: To understand the characteristics of hemorrheological changes in patients with essential hypertension (EH) complicated with lacunar infarction. Methods: The plasma viscosity, high shear viscosity, low shear viscosity and hematocrit of 33 patients with cerebral infarction, 32 patients with EH and 20 controls were measured by Beijing R80 plate viscometer and capillary method. Results: The blood viscosity of EH and infarction group was significantly higher than that of normal control group (P <0.05-0.01). The low shear viscosity, plasma viscosity and hematocrit of infarction group were more significant than those of EH group P <0 0 1). Conclusion: The abnormal increase of blood viscosity may be the important pathogenesis of ischemic cerebrovascular disease.