卵巢早衰（ＰＯＦ）是一种病因复杂，治疗极困难的妇科内分泌疾病。其特点为４０岁以前的妇女出现持续闭经、雌激素水平低下和促性腺激素水平升高。临床表现为程度不同的缺雌症状和生殖器及乳房萎缩。患者多以闭经、不孕及雌激素低下引起的症状就诊。本文对我院有记载的患者中 Premature ovarian failure (POF) is a complicated and extremely difficult treatment of gynecological endocrine diseases. It is characterized by persistent amenorrhea, low estrogen levels and elevated levels of gonadotropins in women 40 years of age. Clinical manifestations of varying degrees of missing female symptoms and genital and breast atrophy. Patients with amenorrhea, infertility and low estrogen symptoms caused by treatment. This article records in our hospital patients