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目的了解2009—2014年新疆涂阳肺结核病患者治疗效果,为完善防控策略提供数据支持。方法对2009—2014年新疆涂阳肺结核病患者的治疗转归情况进行描述性统计分析。结果初治涂阳患者“三位一体”实施前2009—2011年2个月末阴转率由93.94%上升到95.18%,差异有统计学意义(χ2=13.919,P<0.05),实施后2012—2014年阴转率从93.45%下降到85.39%,差异有统计学意义(χ2=285.167,P<0.05);“三位一体”实施前2009—2011年3个月末阴转率由95.74%上升到97.00%,差异有统计学意义(χ2=20.852,P<0.05),实施后2012—2014年阴转率从94.86%下降到88.40%,差异有统计学意义(χ2=265.235,P<0.05);复治涂阳患者“三位一体”实施前2009—2011年2个月末阴转率由94.84%下降到94.02%,差异有统计学意义(χ2=2.706,P<0.05),实施后2012—2014年阴转率下降明显,从93.21%下降到78.94%,差异有统计学意义(χ2=219.406,P<0.05);“三位一体”实施前2009—2011年3个月末阴转率由96.64%下降到95.87%,差异有统计学意义(χ2=5.765,P<0.05),实施后2012—2014年阴转率从94.27%下降到82.22%,差异有统计学意义(χ2=199.105,P<0.05)。结论 “三位一体”新型结核病防治服务体系实施后结核病患者第2和3个月末阴转率有逐年下降趋势,因此需要进一步完善工作模式及结核病防治政策,以保证患者早期、规律、全程、联合、适量化疗方案的完成,提高痰菌阴转率及治愈率。
Objective To understand the therapeutic effect of smear-positive pulmonary tuberculosis in Xinjiang from 2009 to 2014 and to provide data support for perfecting prevention and control strategies. Methods Descriptive statistical analysis of the treatment outcome of smear-positive pulmonary tuberculosis in Xinjiang from 2009 to 2014 was conducted. Results The smear positive rate of smear-positive patients increased from 93.94% to 95.18% at the end of the two months from 2009 to 2011 before implementation. The difference was statistically significant (χ2 = 13.919, P <0.05) The rate of negative conversion decreased from 93.45% to 85.39% in 2014, with a significant difference (χ2 = 285.167, P <0.05). Before the implementation of “Trinity” from 2009 to 2011, the negative conversion rate increased from 95.74% The difference was statistically significant (χ2 = 20.852, P <0.05). The negative conversion rate decreased from 94.86% to 88.40% after 2012-2014. The difference was statistically significant (χ2 = 265.235, P <0.05). The rate of negative conversion decreased from 94.84% to 94.02% at the end of the two months from 2009 to 2011 before the implementation of “Trinity” in the patients with retreatment and smear positive (χ2 = 2.706, P <0.05). After the implementation of 2012-2014 The annual negative conversion rate decreased significantly from 93.21% to 78.94%, the difference was statistically significant (χ2 = 219.406, P <0.05). Before the implementation of “Trinity”, the negative conversion rate from the end of 3 months from 2009 to 2011 was 96.64% (Χ2 = 5.765, P <0.05), and the negative conversion rate decreased from 94.27% to 82.22% after 2012-2014 (χ2 = 199.105, P <0.05), and the difference was statistically significant ). Conclusion After the implementation of the “Trinity” new TB prevention and treatment service system, the negative conversion rates of TB patients at the end of the 2nd and 3rd month have been decreasing year by year. Therefore, it is necessary to further improve the work mode and tuberculosis prevention and control policies so as to ensure the early, regular, full and united patients , The completion of appropriate chemotherapy regimen to improve sputum negative conversion rate and cure rate.