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目的:评价药学干预措施对缺血性脑卒中患者二级预防用药依从性的影响。方法:将某院神经内科收住的418例缺血性脑卒中患者分为干预组和对照组,干预组配备专科临床药师,实施个体化给药、开展床旁用药宣教、发放患者出院用药指导单,对照组不予干预。制定二级预防用药知识和用药依从性调查表,在出院时对2组患者进行用药知识调查,在出院3个月后对2组患者行电话回访进行用药依从性调查。结果:在二级预防用药知识方面,干预组回答为优的比例明显高于对照组,差异有高度统计学意义(P<0.01)。依从性方面干预组明显优于对照组,差异有统计学意义(P<0.05)。结论:临床药师对缺血性脑卒中患者进行药学干预可以增加患者的用药知识、提高二级预防用药依从性。
OBJECTIVE: To evaluate the effect of pharmaceutical interventions on secondary prevention medication adherence in ischemic stroke patients. Methods: One hundred and seventy-four patients with ischemic stroke who were admitted to neurology department of a hospital were divided into intervention group and control group. The intervention group was equipped with specialist clinical pharmacist, and individualized administration was carried out to carry out bedside medication and mission guidance Single, the control group did not intervene. To develop secondary preventive medication knowledge and medication compliance questionnaire, two groups of patients on the discharge of knowledge of medication knowledge, three months after discharge on the two groups of telephone follow-up medication compliance survey. Results: In terms of secondary prevention medication knowledge, the response rate of the intervention group was significantly higher than that of the control group, the difference was highly statistically significant (P <0.01). The compliance group was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion: Pharmacological intervention of clinical pharmacists in patients with ischemic stroke can increase the medication knowledge of patients and improve the compliance of secondary prevention medication.