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目的 探讨介入化疗加放射治疗对晚期中下段食管癌的治疗效果。方法 以顺铂、醛氢叶酸、5 -氟脲嘧啶 (DLF)方案为基础加羟基喜树碱 (HCPT)综合用药 ,采用动脉灌注方法 ,与放射治疗联合使用治疗晚期中下段食管癌。结果 综合治疗组食管癌X线片Ⅰ级率 5 7.1% ,而单纯放疗组为 2 5 .0 % ,有显著性差异 (Ρ <0 .0 5 ) ;以上两组主要毒副反应发生率无显著性差异 (Ρ >0 .0 5 )。结论 介入化疗联合放疗是治疗晚期中下段食管癌较为有效、安全的方法
Objective To investigate the therapeutic effects of interventional chemotherapy and radiation therapy on advanced stage esophageal cancer. Methods HCPT combined with cisplatin, alduronic acid and 5 - fluorouracil (DLF) regimen was used in combination with radiotherapy to treat advanced stage lower esophageal cancer. Results The comprehensive treatment group esophageal cancer X-ray film grade Ⅰ rate of 7.11%, while the radiotherapy group was 25.0%, a significant difference (P <0. 05); the incidence of major side effects in the two groups were no Significant difference (Ρ> 0.05). Conclusion Interventional chemotherapy combined with radiotherapy is an effective and safe method for the treatment of late stage of esophageal cancer