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为研究高甲状腺激素状态下心肌β受体、血浆儿茶酚胺（ＣＡ） 的变化及相互关系，给大鼠口服甲状腺片，平均每只４ ｍｇ／ｄ ，连续６０ ｄ ，检测心室肌β受体密度最大结合量（Ｂｍａｘ） 和血浆儿茶酚胺含量。结果显示，实验组大鼠心肌Ｂｍａｘ（６９ ±１３ ｆｍｏｌ／ｍｇｐｒｏ） 显著低于对照组（９４ ±２２ ｆｍｏｌ／ｍｇｐｒｏ） ；实验组大鼠血浆ＣＡ（ＮＥ：５３０ ±７３ ｐｇ／ｍＬ， Ｅ：１３２ ±６２ ｐｇ／ｍＬ） 显著高于对照组（ＮＥ：３１８ ±１１７ ｐｇ／ｍ Ｌ，Ｅ：９８ ±３６ ｐｇ／ｍＬ） 。提示高甲状腺激素水平作用下，心肌β受体Ｂｍａｘ 下降和血浆ＣＡ 升高是造成心肌损伤的重要原因
To study the changes of myocardial β receptor, plasma catecholamine (CA) and their relationship in hyperthyroidism, the thyroid tablets were orally administered to rats at an average of 4 mg / d for 60 consecutive days. Binding (Bmax) and plasma catecholamine levels. The results showed that the myocardial Bmax (69 ± 13 fmol / mgpro) in the experimental group was significantly lower than that in the control group (94 ± 22 fmol / mgpro); the plasma CA (NE: 530 ± 73 pg / mL, ± 62 pg / mL) was significantly higher than the control group (NE: 318 ± 117 pg / m L, E: 98 ± 36 pg / mL). Prompted the role of high thyroid hormone levels, decreased myocardial B β receptor and elevated plasma CA is an important cause of myocardial injury