目的:分析驻闽某部官兵咽喉反流病(LPRD)的临床特征和相关危险因素。方法:选择驻闽某部官兵3560例,采用整群和分层抽样方法对官兵进行问卷调查。调查内容包括一般人口学资料、反流症状指数量表(RSI)、自行设计的与LPRD相关的饮食、生活及精神心理等影响因素量表。采用Epi Data 3.0软件建立数据库,统计分析官兵LPRD的临床特征和相关危险因素。结果:(1)本次调查3560例官兵中,RSI分值(5.46±6.21)分(0~43分),其中,阳性(罹患LPRD)组374例,占10.5%;阴性(未罹患LPRD)组3186例,占89.5%。阳性组各类症状发生率均非常显著高于阴性组(P<0.01),持续清嗓症状发生率最高,达98.4%。RSI各类症状双变量相关分析结果显示,RSI评分分值除与吞咽受限症状为中等相关(r=0.424)外,与其他症状均为强相关(r>0.5),其中与持续清嗓症状高度相关(r=0.789)。(2)单因素Logistic逐步回归分析结果显示,吸烟、饮酒、常食油腻食物、进食过饱、常食辛辣食物、常食油炸食物、常饮碳酸饮料、常饮咖啡、常饮浓茶、喜甜食、饮食不规律、餐后运动、睡前进食、经常便秘、精神状态不佳、经常睡眠打鼾、经常鼻塞流涕、工作时间过长及经常扁桃体炎等,均可能是LPRD发病的影响因素(P<0.01)。将上述因素纳入多因素Logistic逐步回归分析,结果显示,吸烟、常食油腻食物、常食油炸食物、餐后运动、经常便秘、精神不佳、经常鼻塞流涕、经常扁桃体炎等因素,与LPRD发生相关显著或非常显著(P<0.05,P<0.01,OR值>1);饮酒、进食过饱、常食辛辣食物、常饮碳酸饮料、常饮咖啡、常饮浓茶、喜甜食、饮食不规律、睡前进食、经常睡眠打鼾、工作时间过长等因素,与LPRD发生相关不显著(P>0.05)。结论:驻闽某部官兵LPRD具有一定临床特征,其发病可能受多种因素影响,吸烟、常食油腻食物、常食油炸食物、餐后运动、经常便秘、精神不佳、经常鼻塞流涕、经常扁桃体炎等是官兵发生LPRD的危险因素,应有针对性地采取预防措施,以减少LPRD发生。 Objective: To analyze the clinical characteristics and related risk factors of LPRD in a ministry of Fujian Province. Methods: A total of 3560 officers and soldiers of a ministry stationed in Minnan were selected. The whole army and stratified sampling method were used to survey the officers and men. The survey included general demographic data, RSI scale, self-designed LPRD-related diet, life and psychosocial factors and other influencing factors scale. Epi Data 3.0 software was used to establish a database to statistically analyze the clinical features of LPRDs and related risk factors. Results: (1) RSI score was 5.46 ± 6.21 (0-43) in 3560 officers and soldiers in this survey, of which 374 (10.5%) were positive (with LPRD), negative (without LPRD) 3186 cases, accounting for 89.5%. The incidence of various symptoms in the positive group was significantly higher than that in the negative group (P <0.01), with the highest incidence of persistent throat symptoms (98.4%). Bivariate analysis of various symptoms of RSI showed that RSI scores were strongly correlated with other symptoms (r> 0.5), except moderate correlation with swallowing restricted symptoms (r = 0.424), which was associated with persistent throat symptoms Highly correlated (r = 0.789). (2) Logistic regression analysis showed that smoking, drinking, eating greasy foods, eating too much, eating spicy foods, eating fried foods, drinking carbonated drinks, drinking regular coffee, drinking regular tea, Irregular diet, postprandial exercise, eating at bedtime, frequent constipation, poor mental status, frequent sleep snoring, frequent stuffy nose runny, long working hours and frequent tonsillitis may be the influencing factors of LPRD (P < 0.01). The above factors into the multivariate Logistic stepwise regression analysis showed that smoking, eating greasy food, eating fried foods, postprandial exercise, frequent constipation, poor mental, often stuffy nose runny nose, frequent tonsillitis and other factors, and LPRD occurred (P <0.05, P <0.01, OR> 1); drinking, eating too much, eating regular spicy food, often drink carbonated drinks, regular drink coffee, often drink strong tea, like sweets, irregular diet , Eating at bedtime, frequent sleep snoring, long working hours and other factors were not significantly associated with the occurrence of LPRD (P> 0.05). Conclusion: LPRD in some ministries in Fujian Province has certain clinical features. The incidence of LPRD may be affected by many factors, including smoking, eating greasy food, eating fried foods, postprandial exercise, frequent constipation, poor mental condition, frequent stuffy nose runny nose, frequent Tonsillitis and other officers and soldiers are risk factors for the occurrence of LPRD, should be targeted to take preventive measures to reduce the occurrence of LPRD.