皮肤瘙痒症是一种仅有皮肤瘙痒症状而无原发性皮肤损害的皮肤病[1]。其可以分为泛发性和局限性瘙痒。多见于老年人,多数为良性病程,病因较为复杂,通常认为与气候干燥、过敏、肝肾疾病等有关,但久治不愈的皮肤瘙痒症则可能是恶性肿瘤的首发表现。应引起注意,完善相关检查,尽可能早发现、早诊断、早治疗。笔者报道我院自2000年10月—2012年10月来我科诊治的恶性肿瘤并发皮肤瘙痒症27例。1临床资料1.1一般资料27例患者均为恶性肿瘤并发皮肤瘙痒症,27例患者中男18例,女9例,年龄61~87岁,平均75.2岁。其中胃癌10例,肝癌8例,胰腺 Pruritus is a dermatological condition that has only pruritus and no primary skin lesions [1]. It can be divided into generalized and localized itching. More common in the elderly, most of the benign course, the cause is more complex, usually considered to be dry and allergic, liver and kidney disease, but long-lasting skin pruritus may be the first manifestation of malignant tumors. Should pay attention to improve the relevant checks, as early as possible to find, early diagnosis and early treatment. I report from our hospital since October 2000 - October 2012 to our department for treatment of 27 cases of pruritus and malignant tumor. 1 Clinical data 1.1 General Information 27 patients with malignant tumor complicated pruritus, 27 patients, 18 males and 9 females, aged 61 to 87 years, mean 75.2 years. Including 10 cases of gastric cancer, liver cancer in 8 cases, pancreas