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本文对30例原发性肺癌按照修订后的WHO分类方法进行了尤镜与电镜的对比观察,结果发现9/30例发生类型改变。其中鳞癌为7/12例,小细胞癌为1/4例,腺癌仅1/14例。对低分化及未分化肺癌需依赖电镜识别。电镜下混合癌的比例明显上升,常见的是腺鳞癌,本组为16.7％。这一结果可以解释某些肺癌对放化疗反应的不均一性,也为临床设计综合治疗方案提供更加可靠的组织学依据。
In this paper, 30 cases of primary lung cancer were compared according to the revised WHO classification method. The results showed that 9/30 cases were changed. Among them, squamous cell carcinoma was 7/12 cases, small cell carcinoma was 1/4 case, and adenocarcinoma was only 1/14 cases. For poorly differentiated and undifferentiated lung cancer, electron microscopy is required. Under the electron microscope, the proportion of mixed cancers increased significantly. The common one is adenosquamous carcinoma, which is 16.7% in this group. This result can explain the non-uniformity of radiotherapy and chemotherapy in some lung cancers, and provide more reliable histological basis for the clinical design of comprehensive treatment programs.