白细胞介素(IL)是主要由单个核细胞如活化的T细胞和单核-巨噬细胞等分泌的一类免疫活性因子。免疫系统紊乱是Graves病发生发展的重要因素之一。最近研究证实,IL参与Graves病及Graves眼病免疫紊乱的各个阶段,在其发生机制中具有重要作用。通过纠正IL的表达失衡,调节Graves病免疫自稳,这可能成为Graves病免疫学治疗的新方向。 Interleukins (ILs) are a class of immunocompetent factors that are secreted primarily by mononuclear cells such as activated T cells and monocytes - macrophages. Immune system disorders is an important factor in the development of Graves disease. Recent studies have confirmed that IL involved in Graves disease and Graves ophthalmology immune disorders in all stages, in its pathogenesis has an important role. By correcting the imbalance of IL expression and regulating the immune stability of Graves ’disease, this may become a new direction of immunotherapy of Graves’ disease.