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应用3H－TdR及14C－UR参入淋巴细胞的双标记方法，在体外培养条件下，研究多抗甲素对人淋巴细胞DNA及RNA合成功能的影响。结果表明，在多抗甲素的浓度为0．1～10mg／L时，可显著增强淋巴细胞DNA及RNA的合成功能；当多抗甲素的浓度增至50～100mg／L时，对淋巴细胞合成DNA及RNA的能力呈现抑制作用，3H及14C标记物的参入计数减少。多抗甲素对淋巴细胞DNA及RNA合成功能的影响呈现双相作用。
The dual labeling method of 3H-TdR and 14C-UR into lymphocytes was used to study the effect of polyactin on DNA and RNA synthesis of human lymphocytes in vitro. The results showed that when the concentration of polyactin A was 0.1 ~ 10 mg / L, the synthesis of DNA and RNA of lymphocytes could be significantly enhanced. When the concentration of polyactin A was increased to 50 ~ 100 mg / L, The ability of cells to synthesize DNA and RNA showed inhibition, 3H and 14C markers decreased participation in the count. Polyactin on lymphocyte DNA and RNA synthesis function of biphasic effect.