Multi-proxies of lacustrine sediments, such as total carbon (TC), total organic carbon (TOC), total inorganic carbon (TIC), total nitrogen (TN), total sulfur (TS), hydrogen index (HI), oxygen index (OI) and stable carbon isotopic composition of organic matter (δ 13Corg), were analyzed using a 7.3 m core from Zigê Tangco. The source of the organic matter in the sediment was mainly from autochthonous phytoplankton, therefore the significances of proxies can be interpreted as that high TOC, TOC/TS, HI and δ13Corg values, low TC, TIC values corresponded to warm and wet climatic condition, and vice versa. The process of climatic development in the Zigê Tangco region was hence recovered. During the early and Mid-Holocene, the climate was warm and wet and intensive cold events occurred during the periods of 8600 to 8400 cal a BP and 7400 to 7000 cal a BP. In the second half of Holocene, the climate became cold and dry gradually. The palaeoclimatic process during Holocene in Zigê Tangco region matched well with that in Co Ngoin region which is ca 40 km to the south-east. Therefore this palaeoclimatic process represents the Holocene climatic feature in the Central Tibetan Plateau which has the same pattern in the Northern Tibetan Plateau, but the time and duration of some climatic events might be different. We can conclude that in Holocene solar insolation controlled the climatic pattern on the central Tibetan Plateau. Multi-proxies of lacustrine sediments, such as total carbon (Tc), total organic carbon (TIC), total nitrogen (TN), total sulfur (TS), hydrogen index OI) and stable carbon isotopic composition of organic matter (δ 13Corg), were analyzed using a 7.3 m core from Zigê Tangco. The source of the organic matter in the sediment was mainly from autochthonous phytoplankton, therefore the significances of proxies can be interpreted as that high TOC, TOC / TS, HI and δ13Corg values, low TC, TIC values ​​corresponded to warm and wet climatic conditions, and vice versa. The process of climatic development in the Zigê Tangco region was therefore recovered. During the early and Mid- Holocene, the climate was warm and wet and intensive cold events occurred during the periods of 8600 to 8400 cal a BP and 7400 to 7000 cal a BP. In the second half of Holocene, the climate became cold and dry gradually. The palaeoclimatic process during Holocene in Zigê Tangco r egion matched well with that in Co Ngoin region which is ca 40 km to the south-east. therefore this palaeoclimatic process represents the Holocene climatic feature in the Central Tibetan Plateau which has the same pattern in the Northern Tibetan Plateau, but the time and duration of some climatic events might be different. We can conclude that in Holocene solar insolation controlled the climatic pattern on the central Tibetan Plateau.