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目的 了解糖尿病患者血清睾酮浓度与微血管病变的关系。方法 测定 30例男性糖尿病患者及 34例正常男性血清睾酮、黄体生成素、卵泡刺激素、泌乳素、雌二醇 ,比较观察糖尿病患者垂体—性腺轴变化。结果糖尿病血清睾酮水平明显低于对照组 ,糖尿病患者中睾酮水平减低组的微血管病变的发生率明显高于睾酮水平正常组 ,其血清黄体生成素水平明显高于血清睾酮水平正常组 ,提示微血管病变在糖尿病患者垂体—性腺轴变化中有一定影响
Objective To understand the relationship between serum testosterone concentration and microangiopathy in diabetic patients. Methods Serum testosterone, luteinizing hormone, follicle stimulating hormone, prolactin and estradiol were measured in 30 male patients with diabetes mellitus and 34 normal male patients. The changes of pituitary - gonad axis in diabetic patients were compared. Results The level of serum testosterone in diabetic patients was significantly lower than that in the control group. The incidence of microvascular lesions in testosterone-reduced diabetic patients was significantly higher than that in normal testosterone group, and serum LH levels were significantly higher than those in normal testosterone group, suggesting that microvascular disease Diabetes in the pituitary - gonadal axis changes have a certain impact