有研究表明,炎症参与了动脉粥样硬化的发生和发展,其发病机制主要涉及细胞外基质(ECM)降解和血管壁重构,炎症介质可刺激血管平滑肌细胞促使其分泌组织蛋白酶S、K和半胱氨酸蛋白酶等。半胱氨酸蛋白酶具有促弹性组织离解特性,它可在血管动脉弹力蛋白损伤处过度表达。血清胱抑素C(Cys C)在体内能较强抑 Some studies have shown that inflammation is involved in the occurrence and development of atherosclerosis. Its pathogenesis mainly involves the degradation of extracellular matrix (ECM) and the remodeling of blood vessel wall. Inflammatory mediators can stimulate vascular smooth muscle cells to promote the secretion of cathepsin S, K and Cysteine ​​protease and so on. Caspases have pro-elastolytic dissociation properties that can be overexpressed at the arteriolar elastin lesions. Serum cystatin C (Cys C) in the body can be more suppressed