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目的动态观察尼莫地平对高血压脑出血患者局部脑血流量,脑水肿和临床疗效的观察。方法将54例高血压脑出血患者随机分为对照组和尼莫地平治疗组,行CT扫描及临床疗效的动态观察,并随机从对照组和治疗组中分别抽出10例患者行CT的动态观察,图像的处理和临床疗效的评定采用盲法分析。结果治疗组在CT水肿带和临床疗效的改善显著优于对照组。结论尼莫地平不仅改善高血压脑出血后局部脑血流量和临床疗效,而且减轻血肿周围水肿的范围。
Objective To observe the effect of nimodipine on regional cerebral blood flow, cerebral edema and clinical curative effect in patients with hypertensive intracerebral hemorrhage. Methods Fifty-four patients with hypertensive intracerebral hemorrhage were randomly divided into control group and nimodipine group. CT scan and dynamic clinical observation were performed. Ten cases were randomly divided into control group and treatment group. CT dynamic observation , Image processing and evaluation of clinical efficacy using blind analysis. Results The improvement of CT edema zone and clinical efficacy in the treatment group was significantly better than that in the control group. Conclusion Nimodipine not only improves local cerebral blood flow and clinical curative effect after hypertensive intracerebral hemorrhage, but also reduces the range of edema around hematoma.