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目的探讨奥美拉唑联合莫沙必利应用于食管癌术后反流性食管炎的疗效。方法回顾自2006年5月-2008年5月因食管癌所行食管胃吻合术后有食管反流症状的患者240例,分为单服奥美拉唑组和奥美拉唑联合莫沙必利组进行疗效对比。结果治疗组和对照组临床症状评价总有效率分别为94.17%、70%,治疗组优于对照组,差异有统计学意义(P<0.05)内镜下评价总有效率分别为88.33%、85.83%。结论奥美拉唑联合莫沙必利治疗食管癌术后反流性食管炎是一种确切、经济、有效的办法。
Objective To investigate the curative effect of omeprazole combined with mosapride on reflux esophagitis after esophagectomy. Methods From May 2006 -2008 in May due to esophageal cancer esophageal anastomosis after esophageal reflux symptoms in patients with 240 cases, divided into single-dose omeprazole group and omeprazole combined with mosapride Lee group for efficacy comparison. Results The total effective rate of clinical symptom evaluation in treatment group and control group was 94.17% and 70%, respectively. The treatment group was superior to the control group with statistically significant difference (P <0.05). The total effective rates of endoscopic evaluation were 88.33% and 85.83 %. Conclusion omeprazole combined with mosapride in the treatment of postoperative esophageal reflux esophagitis is an accurate, economical and effective way.