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目的探讨脓毒性休克患儿液体复苏的临床意义。方法选择符合诊断标准的72例感染性休克患儿作为研究对象,其中好转存活36例,死亡36例;利用SPSS15.0的logistic回归分析对两组的收缩压、舒张压、平均动脉压、pH和入院24h尿量进行分析。结果感染性休克的病死率高达50%,死亡组的收缩压、舒张压、平均动脉压、pH和入院24h尿量与存活组比较差异有统计学意义。logistic回归分析中,模型检验X2=26.781,p=0.000,模型有统计意义。入院24h尿量、平均动脉压是危险因素(OR值、95%可信区间分别为5.197,1.359～19.878;1.125,1.025～1.234)。结论早期液体复苏能有效地改善循环与组织灌注,是脓毒性休克患儿抢救成功与否的重要因素之一。
Objective To investigate the clinical significance of fluid resuscitation in children with septic shock. Methods Seventy-two children with septic shock were enrolled in this study. Thirty-six survived and 36 died. Logistic regression analysis was used to analyze the systolic blood pressure, diastolic blood pressure, mean arterial pressure, pH And 24h urine output for analysis. Results The mortality rate of septic shock was as high as 50%. The systolic blood pressure, diastolic blood pressure, mean arterial pressure, pH and urine output at admission were significantly different from those in survivors in death group. Logistic regression analysis, the model test X2 = 26.781, p = 0.000, the model has statistical significance. Urine volume at admission and mean arterial pressure were risk factors (OR, 95% confidence interval, 5.197, 1.359-19.878, 1.125, 1.025-1.234, respectively). Conclusion Early liquid resuscitation can effectively improve circulation and tissue perfusion, which is one of the important factors in the success of resuscitation in children with septic shock.