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目的 :探索紫松果菊对荷瘤小鼠的抑瘤及产生肿瘤坏死因子 (TNF)的作用。 方法 :测量小鼠荷S180 瘤株前后体重及瘤重 ,微量NAG释放法测血清TNF。结果 :紫松果菊对小鼠S180 没有抑瘤效应 ,但能明显降低荷瘤小鼠产生TNF的水平。结论 :紫松果菊有抑制小鼠产生TNF的作用 ,因此可能具有抗炎和抗过敏的作用。
Objective: To explore the effect of Echinacea on inhibiting tumor and producing tumor necrosis factor (TNF) in tumor-bearing mice. Methods: The body weight and tumor weight of mice bearing S180 tumor were measured before and after treatment. The levels of TNF in serum were measured by the method of NAG release. Results: Echinacea had no antitumor effect on mouse S180, but could significantly reduce the level of TNF produced by tumor-bearing mice. Conclusion: Echinacea has inhibitory effect on the production of TNF in mice and therefore may have anti-inflammatory and anti-allergic effects.