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目的观察探讨倍他乐克治疗慢性心衰的效果及不良反应。方法本院收治的68例慢性收缩性心衰患者,其中心功能Ⅱ级18例、Ⅲ级40例、Ⅳ级10例,均口服倍他乐克治疗4周,观察心功能的临床改善情况。结果疗程结束后,观察本组慢性心衰患者的平均心率、舒张压及收缩压、左室射血分数(LVEF)、左室舒张末期内径(LVDd)均明显优于治疗前(P<0.05)。结论倍他乐克治疗慢性心衰患者效果显著、安全,值得临床关注。
Objective To investigate the effect and adverse reactions of Betaloc on chronic heart failure. Methods Sixty-eight patients with chronic systolic heart failure admitted to our hospital were enrolled in this study. Their central function was grade Ⅱ in 18 cases, grade Ⅲ in 40 cases and grade Ⅳ in 10 cases. All patients were treated with metoprolol orally for 4 weeks to observe the clinical improvement of cardiac function. Results After treatment, the average heart rate, diastolic blood pressure and systolic blood pressure, left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter (LVDd) in patients with chronic heart failure were significantly better than those before treatment (P <0.05) . Conclusion Betaloc therapy in patients with chronic heart failure with significant results, safety, deserves clinical attention.