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动物药理实验结果表明左金丸水提液能促使实验性大白鼠胃小弯溃疡的愈合,愈合率93.33%,明显高于雷尼替丁(P<0.05)及生理盐水(P<0.005)对照组。在幽门结扎术大白鼠左金丸明显抑制胃液分泌,与雷尼替丁和生理盐水比较,其差异有非常显著性(P<0.05及P<0.001).在胃窦移植于结肠术大白鼠获得类似结果,这可能是其抗溃疡作用机理之一。
The results of animal pharmacological experiments showed that Zuojin Pill extract can promote the healing of gastric minor ulcers in experimental rats, and the healing rate was 93.33%, which was significantly higher than that of ranitidine (P<0.05) and normal saline (P<0.005) in the control group. . In the pylorus ligation Dazuzu Zuojin Pills significantly inhibited the secretion of gastric juice, compared with ranitidine and saline, the difference was very significant (P <0.05 and P <0.001). Similar results were obtained in gastric antrum transplantation in rats As a result, this may be one of its antiulcerative mechanisms.