氯喹虽已广泛应用于疟疾及慢性风湿样疾病的治疗,但长期服药会发生不可逆性的视网膜病及斑点病等严重并发症及可逆性的心肌损害、胃肠道紊乱及白发等。虽然尚未见有关氯喹副作用与其总剂量或血浓度间相互关系的报道,但认为副反应的发生率与剂量有关。为此,作者观察了100例服用氯喹病人的副反应发生率及其类型,并测定其血 Although chloroquine has been widely used in the treatment of malaria and chronic rheumatoid diseases, long-term medication can cause irreversible retinopathy and speckle and other serious complications and reversible myocardial damage, gastrointestinal disorders and white hair. Although there have been no reports of the correlation between the side effects of chloroquine and its total dose or blood concentration, the incidence of side effects is dose related. To this end, the authors observed the incidence of side effects in 100 patients taking chloroquine and its type, and determine the blood