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目的:探索孤独症谱系障碍(autism spectrum disorder,ASD)学龄前男童局限性兴趣的特征,为其行为矫正及康复训练提供参考。方法:纳入符合入组标准的50名ASD男童及52名年龄匹配的正常男童,采用儿童孤独症评估量表(childhood autism rating scale,CARS),孤独症诊断观察量表(autism diagnostic observation schedule,ADOS),孤独症诊断访谈量表修订版(autism diagnostic interview-revised,ADI-R)和格赛尔发育量表(Gesell developmental schedule,GDS)进行调查。利用Tobii Pro X3-120眼动仪记录捕捉眼动轨迹特征,使用IBM SPSS Statistics 20.0软件进行统计分析,对正常发育组和ASD组在视觉搜索任务中的眼动特征数据进行独立样本n t检验,并把有差异的眼动特征数据和临床症状进行相关分析。n 结果:ASD组CARS总分为(34.13±4.59)分、ADOS总分为(14.44±2.59)分和ADI-R总分为(39.91±12.11)分。ASD儿童眼动表现显示出局限性兴趣特点,ASD儿童探索物体总数[(9.28±2.72)个]显著低于正常儿童[(12.67±2.45)个],差异有统计学意义(n t=6.610,n P<0.01);ASD儿童探索每个物体时长[(0.67±0.37)ms]显著高于正常儿童[(0.54±0.15)ms],差异有统计学意义(n t=-2.363,n P=0.021);ASD儿童探索每个物体次数[(2.80±1.00)次]显著高于正常儿童[(2.48±0.48)次],差异有统计学意义(n t=-2.360,n P=0.021)。相关分析发现ASD儿童探索物体的个数与ADOS总分(n r=-0.480,n P<0.01)、CARS总分(n r=-0.487,n P<0.01)、ADOS评分中沟通交流分项(n r=-0.290,n P=0.041)、ADOS评分中社会交往能力分项(n r=-0.491,n P<0.01)、ADOS评分中游戏能力分项(n r=-0.397,n P=0.004)和ADI-R评分中的沟通交流分项(n r=-0.331,n P=0.025)均呈负相关。n 结论:ASD儿童眼动表现显示出局限性兴趣特点,表现为探索物体更少,更固着,细节搜索更多,并且ASD儿童的症状越重,其探索物体的数目越少,局限性兴趣越固着。“,”Objective:To explore the characteristics of eye tracking movement on circumscribed interests in preschool children with autism spectrum disorder (ASD), providing some reference for behavior correction and rehabilitation training.Methods:Fifty ASD children and fifty-two age-matched typically developing children(TDC) were investigated by the childhood autism rating scale(CARS), the autism diagnostic observation schedule(ADOS), the autism diagnostic interview-revised (ADI-R) and Gesell Developmental Schedule, (GDS). Eye movement during the visual search task was captured by the Tobii Pro X3-120 eye tracker.All data were analyzed by the IBM SPSS Statistics 20.0.Eye movement patterns were compared between TDC and ASD children using the independent-sample n t test, and the correlations were then analyzed between abnormal eye movement characteristics and their core syndrome.n Results:The total scores of CARS, ADOS and ADI-R in ASD group were 34.13±4.59, 14.44±2.59 and 39.91±12.11 respectively.During passive viewing of complex non-social picture arrays, ASD and TDC group explored total number of images were 9.28±2.72 and 12.67±2.45.The fixation time per image explored in ASD and TDC group were (0.67±0.37)ms and (0.54±0.15)ms.Moreover, the number of discrete fixations per image explored in ASD and TDC group was 2.80±1.00 and 2.48±0.48.Compared with the TDC group, ASD children demonstrated circumscribed attention (n t=6.610, n P<0.01) with more perseveration (n t=-2.363, n P=0.021) and detail-orientation (n t=-2.360, n P=0.021). Exploration was negatively correlated with the total score of ADOS (n r=-0.480, n P<0.01), CARS (n r=-0.487, n P<0.01), communication score of ADOS(n r=-0.290, n P=0.041), social score of ADOS(n r=-0.491, n P<0.01), game score of ADOS(n r=-0.397, n P=0.004)and communication score of ADI-R(n r=-0.331, n P=0.025)in the ASD group.n Conclusion:Compared with TDC, the eye movement pattern shows the circumscribed interests of ASD children, who not only explore fewer objects but also demonstrate circumscribed attention with more perseveration and detail-orientation.Moreover, the more severe the symptoms of ASD children, the fewer objects the children explore and the more stereotyped the circumscribed interest.